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Engineered RNase Inhibitor

SKU: E-0075

Description

Engineered RNase Inhibitor binds to ribonucleases A, B, and C in a 1:1 stoichiometry with femtomolar affinity and renders them unable to bind or degrade RNA. Engineered RNase Inhibitor has significantly improved resistance to oxidation compared to the human/porcine RNase inhibitors and is stable at low DTT concentrations.

The provided pack sizes are configured to run 25 rxns or 250 rxns of 100-μL IVT, following our recommended co-transcriptional protocol to produce Cap-1 mRNAs. Please see the details in the product insert. The 60 µg and 530 µg pack sizes contain approximately 3,000 units and 26,500 units of enzymes, respectively.

Unit definition: One unit of the enzyme inhibits the activity of 5 ng of RNase A by 50%.

Product details
Catalog No E-0075
Concentration 0.8 mg/mL
Buffer 20 mM HEPES-KOH
Volume 75μL
Recommended Storage -20 to -25°C
Reaction Size 25.0

Technical documents

Product FAQs

ISO 13485 compliant.

Yes

Recommended final concentrations 1U/mL

Certificate of analysis

Intellectual property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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