2'-O-Methyladenosine-5'-Triphosphate
Description
2'-O-Methyladenosine-5'-Triphosphate is an ATP analog which is methylated at the 2'-O position of the ribose sugar. Methylation at this position results in increased stability of the resulting RNA strand against base hydrolysis and nuclease cleavage. This makes it a useful NTP for aptamer synthesis where increased variation in nucleotide composition along with increased nuclease resistance are desired.
Product details
| Catalog No | N-1015 |
| Purity | ≥95% by AX-HPLC |
| Extinction Coefficient | 15 |
| Molecular Formula | C₁₁H₁₈N₅O₁₃P₃ (free acid) |
| Molecular Weight | 521.20 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H₂O |
| Recommended Storage | -20°C or below |
| Application | Aptamers |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Adenosine |
| Nucleotide Category | Sugar Modified |
| Shipping Temp | Frozen |
| Sugars | 2'-O-Methyl |
Technical documents
- Safety Data Sheet Look-up open_in_new
Certificate of analysis
- Certificate of Analysis (CoA) open_in_new
Intellectual property
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