Inosine-5'-Triphosphate
SKU: N-1020
Description
Adenosine deamination is catalyzed by an enzyme called adenosine deaminase acting on RNA (ADAR), and results in the formation of inosine in a process called A-to-I RNA editing. RNA editing plays a crucial role in RNA metabolism, splicing, nuclear export and localization. Inosine 5'-triphosphate (ITP) also functions as an alternative substrate for ATPases and GTPases and has been used to study activation and binding kinetics of nucleoside interaction with various ATPases and GTPases.
Product details
| Catalog No | N-1020 |
| Purity | ≥98% by AX-HPLC |
| Extinction Coefficient | 12 |
| Molecular Formula | C₁₀H₁₅N₄O₁₄P₃ (free acid) |
| Molecular Weight | 508.10 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H₂O |
| Recommended Storage | -20°C or below |
| Application | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Inosine |
| Nucleotide Category | Base Modified RNA |
| Shipping Temp | Frozen |
| Sugars | RNA |
Technical documents
- Safety Data Sheet Look-up open_in_new
Certificate of analysis
- Certificate of Analysis (CoA) open_in_new