2', 3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate)
Description
2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddTTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
Product details
| Catalog No | N-8012 |
| Purity | ≥90% by AX HPLC |
| Extinction Coefficient | 9650 L⋅mol-1⋅cm-1 |
| Molecular Formula | C10H17N2O12P3S |
| Molecular Weight | 482.2 g/mole |
| Salt Form | Li+ |
| Concentration | 100mM |
| Buffer | H2O |
| Recommended Storage | -20°C ± 5°C |
| Sugar Classification | ddNTP |
| Base Analog(s) | Thymidine |
| Nucleotide Category | Phosphate Modified |
| Shipping Temp | Frozen |
| Modifications | Thio-triphosphate |
| Synonyms | (1-Thio)-ddTTP |
Technical documents
- Safety Data Sheet Look-up open_in_new
Certificate of analysis
- Certificate of Analysis (CoA) open_in_new
Intellectual property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.
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