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2', 3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate)

SKU: N-8012

Description

2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddTTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

Product details


Catalog No	N-8012
Purity	≥90% by AX-HPLC
Extinction Coefficient	9
Molecular Formula	C₁₀H₁₇N₂O₁₂P₃S (free acid)
Molecular Weight	482.20 g/mole (free acid)
Salt Form	Li+
Concentration	100 mM
Buffer	H₂O
Recommended Storage	-20°C or below
Backbone	5'-O-(1-Thiotriphosphate)
Base Analog(s)	Thymidine
Nucleotide Category	Phosphate Modified
Shipping Temp	Frozen
Sugars	3'-Deoxy

Technical documents

Safety Data Sheet Look-up

Certificate of analysis

Certificate of Analysis (CoA)

Intellectual property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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