2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)

SKU: N-8009

Description

2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

Product details

Catalog No N-8009
Purity ≥90% by AX-HPLC
Extinction Coefficient 15
Molecular Formula C₁₀H₁₆N₅O₁₀P₃S (free acid)
Molecular Weight 491.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H₂O
Recommended Storage -20°C or below
Backbone 5'-O-(1-Thiotriphosphate)
Base Analog(s) Adenosine
Nucleotide Category Phosphate Modified
Shipping Temp Frozen
Sugars 2'-3'-Dideoxy

Technical documents

Certificate of analysis

Intellectual property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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