6-Thio-2'-deoxyguanosine-5'-Triphosphate
SKU: N-2045
Description
The nucleoside analogue 6-thio-2’-deoxyguanosine (6-thio-dG) is a substrate for telomerase and is incorporated into de novo synthesized telomeres. This results in modified telomeres, leading to telomere dysfunction in cells expressing telomerase, such as cancer cells.
Product details
| Catalog No | N-2045 |
| Purity | ≥90% by AX-HPLC |
| Extinction Coefficient | 24 |
| Molecular Formula | C₁₀H₁₆N₅O₁₂P₃S (free acid) |
| Molecular Weight | 523.20 g/mole (free acid) |
| Salt Form | Li+ |
| Concentration | 100 mM |
| Buffer | H₂O |
| Recommended Storage | -20°C or below |
| Application | Aptamers |
| Backbone | 5'-Triphosphate |
| Base Analog(s) | Guanosine |
| Nucleotide Category | Base Modified DNA |
| Shipping Temp | Frozen |
| Sugars | DNA |
Technical documents
- Safety Data Sheet Look-up open_in_new
Certificate of analysis
- Certificate of Analysis (CoA) open_in_new
Intellectual property
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