7-Deaza-2'-deoxyguanosine-5'-Triphosphate

SKU: N-2011

Description

This deoxyguanosine analog lacks the N7 nitrogen found in the natural guanine nucleobase. Replacement of this nitrogen atom with a carbon atom results in diminished structure of the major groove in DNA and may disrupt base stacking, but does not interfere with Watson-Crick base pairing. This is desirable for applications such as amplification and sequencing of GC-rich nucleic acid sequences.

Product details

Catalog No N-2011
Purity ≥95% by AX-HPLC
Extinction Coefficient 10
Molecular Formula C₁₁H₁₇ N₄O₁₃P₃ (free acid)
Molecular Weight 506.00 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H₂O
Recommended Storage -20°C or below
Application Aptamers
Backbone 5'-Triphosphate
Base Analog(s) Guanosine
Nucleotide Category Base Modified DNA
Shipping Temp Frozen
Sugars DNA

Technical documents

Certificate of analysis

Intellectual property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission from TriLink No license under any patent or other intellectual property right of TriLink or its licensors is granted or implied by the purchase unless otherwise provided in writing.